Xerosis, or dry skin, is a common phenomenon in older adults, particularly affecting the lower legs. This condition often causes discomfort and can impede mobility, leading to a greater likelihood of skin infections and eczema. A recently conducted observational study focused on the impact of a 10% urea-based moisturizing lotion on individuals aged 60 to 75 years suffering from moderate to severe lower-leg xerosis. The study included 59 participants who applied the lotion twice daily for four weeks, followed by evaluations by healthcare professionals on hydration, skin texture, and barrier function.

Results from the study after the four-week application period indicated a significant improvement in various clinical evaluation metrics. Physicians observed marked enhancements in several symptoms, such as overall xerosis, skin roughness, dryness, and total severity of the xerosis on the lower legs. Notably, reductions were recorded not only in erythema and lichenification but also in desquamation and affected body surface area, suggesting that the benefits extend beyond mere cosmetic improvements. Instrument-based corneometry further demonstrated reduced trans-epidermal water loss, which aligns with improved skin barrier function resulting from sustained use of the lotion.

Patient-reported outcomes collected at both one and four weeks post-treatment highlighted the tangible benefits experienced by participants, who reported enhanced quality of life and relief from the discomfort associated with dry skin. Many patients noted a marked reduction in symptoms that were previously interfering with their daily activities, reinforcing the lotion's effectiveness as a practical, non-invasive treatment option for age-related xerosis and itching.

For clinicians, these findings advocate for the inclusion of a 10% urea moisturizing lotion in standard skin care routines for older adults dealing with severe xerosis on the lower legs. The consistent data on clinical improvements and patient satisfaction gathered throughout the observational study suggest that this lotion not only aids in restoring skin barrier function but also significantly enhances overall symptom relief. Integrating this treatment into regular practice could provide a reliable solution for managing xerosis in this demographic and address their specific skin care needs effectively.